Deployment of an Autonomous Underwater Vehicle in Ice-covered Sea of Okhotsk : The First Japanese Challenge

第3回極域科学シンポジウム/第35回極域気水圏シンポジウム 11月29日（木） 国立国語研究所 ２階多目的

Development Status of Compact X-band Synthetic Aperture Radar Compatible with a100kg-class SAR Satellite and Its Future Plan

We have proposed a novel SAR system compatible with a 100kg-class small satellite. This SAR development is funded for four years (2016-2019) by Japanese government. At present we are developing engineering model (EM). This paper describes the EM test preliminary results and the future plan. The specifications of SAR observation are single polarization SAR with 1m ground resolution at minimum. A size of the satellite is 0.7m x 0.7m x 0.7m on a rocket. A size of the deployed antenna is 4.9m x 0.7m. Novel parallel-plate slotted array antennas made of honeycomb panel have been developed. Six outputs from GaN HEMT power amplifiers are combined in a waveguide resonator and 1 kW RF transmitting power is fed to the antenna trough non-contact choke flanges at deployable hinges (patented)

RhoA activation participates in rearrangement of processing bodies and release of nucleated AU-rich mRNAs

Cytoplasmic ribonucleoprotein granules, known as processing bodies (P-bodies), contain a common set of conserved RNA-processing enzymes, and mRNAs with AU-rich elements (AREs) are delivered to P-bodies for translational silencing. Although the dynamics of P-bodies is physically linked to cytoskeletal network, it is unclear how small GTPases are involved in the P-body regulation and the ARE-mRNA metabolism. We found here that glucose depletion activates RhoA GTPase and alters the P-body dynamics in HeLa cells. These glucose-depleted effects are reproduced by the overexpression of the RhoA-subfamily GTPases and conversely abolished by the inhibition of RhoA activation. Interestingly, both RhoA activation and glucose depletion inhibit the mRNA accumulation and degradation. These findings indicate that RhoA participates in the stress-induced rearrangement of P-bodies and the release of nucleated ARE-mRNAs for their stabilization

Bathymetry Mapping at Kuroshima Knoll with Synthenic Aperture of Interferometry Sonar

特集1 海中工学研究センタ

Exploration of NW Rota 1 Underwater Volcano by Autonomous Underwater Vehicle "r2D4"

特集1 海中工学研究センタ

Developments in Viral Vector-Based Vaccines

Viral vectors are promising tools for gene therapy and vaccines. Viral vector-based vaccines can enhance immunogenicity without an adjuvant and induce a robust cytotoxic T lymphocyte (CTL) response to eliminate virus-infected cells. During the last several decades, many types of viruses have been developed as vaccine vectors. Each has unique features and parental virus-related risks. In addition, genetically altered vectors have been developed to improve efficacy and safety, reduce administration dose, and enable large-scale manufacturing. To date, both successful and unsuccessful results have been reported in clinical trials. These trials provide important information on factors such as toxicity, administration dose tolerated, and optimized vaccination strategy. This review highlights major viral vectors that are the best candidates for clinical use

Potential characterization of free-space-wave drop demultiplexer using cavity-resonator-integrated grating input/output coupler

A prototype free-space-wave drop demultiplexer consisting of a cavity-resonator-integrated grating input/output coupler (CRIGIC) and a different-guided-mode-coupling distributed Bragg reflector (DGM-DBR) was designed for constructing a high-density wavelength-division-multiplexing intra-board chip-to-chip optical interconnection. The CRIGIC consists of one grating coupler and two DBRs, and can vertically couple a guided wave and a free-space wave with high efficiency. A two-channel drop demultiplexer operating at around 850-nm wavelength with 5-nm channel spacing in wavelength was fabricated in a thin-film SiO2-based waveguide. The device performance was predicted theoretically, characterized experimentally, and discussed